CRP'NÝN AKUT KARIN TANISINDAKÝ YERÝ

Kliniðimizde 1.6.1994-1.6.1995 tarihleri arasýnda, nontravmatik akut karýn ön tanýsý ile yatýrýlýp tedavi edilen toplam 107 hastada preoperatif ve postoperatif 24, 48, 72'ci saatlerde plazma CRP (C-Reaktif Protein) düzeyleri incelendi. Opere edilen 89 hastada akut karýna yol açan cerrahi bir patoloji vardý. Bunlar çalýþma grubunu oluþturdu. Akut karýn ön tanýsý ile yatýrýlýp yapýlan gözlem sonucu rahatlayan ve akut karýn ön tanýsýyla operasyona alýnýp cerrahi bir patoloji tesbit edilemeyen 18 hasta ise kontrol grubunu oluþturdu. CRP deðerleri 6 mg/L'den yüksek ise anlamlý olarak kabul edildi. Çalýþma grubunda 89 hastanýn 80'inde (%89.8); kontrol grubunda ise 18 hastanýn 4'ünde (%22.2) CRP deðerleri 6 mg/L'den yüksek olarak bulundu. Çalýþma grubunda preoperatif CRP deðerleri 6 mg/L'den yüksek olarak bulundu. Çalýþma grubunda preoperatif CRP deðerleri kontrol grubuna göre çok anlamlý derecede yüksekti. Akut karýn hastalýklarý içinde de en yüksek preoperatif CRP deðerleri akut apandisitti hastalarda tesbit edildi. Çalýþma grubunda 48'ci saatteki postoperatif CRP deðerlerinin preoperatif ve diðer postoperatif deðerlerden daha yüksek olduðu, kontrol grubunda ise preoperatif ve postoperatif CRP deðerleri arasýnda önemli fark olmadýðý görüldü. Yaptýðýmýz çalýþma sonucunda cerrahi akut karýn hastalarýnda preoperatif dönemde CRP'nin yükseldiðini ve postoperatif erken dönemde bu yüksekliðin devam ettiðini tesbit ettik.

DIAGNOSTIC VALUE OF CRP IN ACUTE ABDOMEN

Serum C-reactive protein was measured preoperatively and postoperatively 24, 48 and 72nd hours in 107 patients hospitalized with the diagnosis of nontraumatic acute abdomen in our clinic between 1.6.1994 and 1.6.1995. Eighty-nine of the patients formed the study group. Eighteen patients who did not have a surgical pathology in the operation or who recovered after the observation period formed the control group. CRP values higher than 6mg/L were regarded as significant. In the study group, 80 patients (89.8%) and in the control group, 4 patients (22.2: ) had CRP values higher than 6mg/L. Preoperative CRP value of the study group was significantly higher than that of the control group. The highest preoperative CRP value was found in the patients with acute appendicitis in the study group. In the study group, CRP value measured at the 48th hour postoperatively was higher than those measured preoperatively and 24th and 72nd hours postoperatively. In the control group, there was not a difference between CRP values measured preoperatively and postoperatively. We concluded that CRP values are high in the preoperative and early postoperative period in the patients with acute abdomen.