The histopathological investigation of the effect on regional and systemic tissues of the application of Medicinal Plant Extract Ankaferd Blood Stopper in deep tissue injuries in Rats

Purpose:
This study was planned to evaluate the hystopathological changes under light microscope when the ABS (mixture of five plant extracts) was applied in deep tissue hemorrhage and the systemic organ effects as animal study model.
Materials and Methods:
A total of 50 Wistar Albino rats were divided into 5 groups each consisting 10 rats. The rats underwent femoral vein puncture and treated with ABS tampon, ABS spray, Surgicel and one group left untreated. After 2 weeks, each group underwent partial tissue excision in the same femoral region and as well as from brain, heart, kidney and liver.
Results:
The specimens from all group was obtained from femoral region after two weeks and evaluated under light microscope. The light microscope revealed any histopathological changes on neurovascular structures or in deep connective tissues in all groups.
Conclusions:
Ankaferd Blood Stopper provided hemostasis and was observed to stop bleeding. There were any hystopathological changes in tissue level and no pathological effects in other organs tissues under light microscope, the remote organ tissue remain clear.