2 octyl-cyanoacrylate glue for Fixation of STSG in genitourinary tissue defects due to Fournier gangrene: A Preliminary Trial

Background: In these first reported series we observed the outcomes of skin take and wound healing using 2-octyl-cyanoacrylate glue which was used as tissue glue in the reconstruction of complex genital skin loss due to fournier gangrene.
Material and Methods: Fifteen patients with Fournier’s gangrene were treated in this study. After initial surgical debridement, all defects were repaired using STSG. In this method a thin layer of 2 octyl-cyanoacrylate was dripped on the recipient site immediately before graft application. All wounds were followed up postoperatively and observed for evidence of graft take, seroma or hematoma formation, drainage, and infection. Patient and physician satisfaction were also determined.
Results: Grafts were completely accepted in all fifteen patients. None of the patients had wound infection, seroma, hematoma, or other complications.
Conclusions: Use of 2 octyl-cyanoacrylate glue (Glueseal) for STSG fixation in complex genital skin defects after fournier gangrene may be an acceptable alternative to conventional surgical closure with a good cosmetic outcome. Further studies are needed to confirm our initial success with this approach.
Key words: cyanoacrylate, skin graft, fournier gangrene.