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Prophylactic injection therapy is necessary for Forrest type 2b duodenal ulcers. [Ulus Travma Acil Cerrahi Derg]
Ulus Travma Acil Cerrahi Derg. 2013; 19(1): 29-32 | DOI: 10.5505/tjtes.2013.88220

Prophylactic injection therapy is necessary for Forrest type 2b duodenal ulcers.

Osman Zekai Oner1, Murat Gonenc2, Mustafa Uygar Kalayci2, Mehmet Abdussamet Bozkurt2, Selin Kapan3, Halil Alis2
1Antalya Training And Research Hospital
2Dr. Sadi Konuk Training And Research Hospital
3Kanuni Sultan Suleyman Training And Research Hospital

Objective: To assess the effect of prophylactic injection therapy during the index
gastroscopy on upper gastrointestinal bleeding due to Forrest type 2b duodenal ulcer.
Methods: The patients who were admitted with upper gastrointestinal bleeding and
who had emergency gastroscopy between January 2004 and January 2011 were
retrospectively recruited to the study. Among those, the patients with Forrest type 2b
duodenal ulcer were selected and divided into two groups. The patients in Group 1 had
only diagnostic gastroscopy, whereas those in Group 2 had prophylactic injection therapy
during the index gastroscopy.
Results: Eighty seven patients were included to the study. There were 41 patients in
Group 1 and 46 patients in Group 2. There was a significant difference in the incidence
of rebleeding (26.8% versus 6.5%, p=0.017). The mortality rate was similar in both
groups (9.7% versus 2.1%, p=0.184).
Conclusion: We recommend prophylactic injection therapy in patients with upper
gastrointestinal bleeding who have Forrest type 2b duodenal ulcer.

Keywords: Gastrointestinal bleeding, Forrest classification, rebleeding, mortality, injection therapy.

Corresponding Author: Murat Gonenc, Türkiye
Manuscript Language: English
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