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Intestinal perforation in Wegener’s granulomatosis: a case report [Ulus Travma Acil Cerrahi Derg]
Ulus Travma Acil Cerrahi Derg. 2005; 11(4): 348-351

Intestinal perforation in Wegener’s granulomatosis: a case report

Tamer Akça1, Tahsin Çolak1, Mehmet Çağlıkülekçi1, Koray Öcal1, Suha Aydın1
Mersin University, Faculty of Medicine, Department of General Surgery, Mersin, Turkey

Wegener's granulomatosis is a disease characterized by a necrotizing vasculitis and granulomatous inflammation. The localized form involves the upper and/or lower respiratory tracts while in the common generalized form there is a widespread necrotizing vasculitis and renal involvement. Although gastrointestinal involvement which has been detected at necropsy in 24% of the cases is an uncommon finding, it might cause severe complications. We report a patient with clinical Wegener’s granulomatosis who subsequently developed gastrointestinal perforation. Gastrointestinal perforation was treated with surgical resection and the patient survived under the treatment of cyclophosphamide and prednisolone with no further gastrointestinal complications. The present case indicates that the gastrointestinal complications might be considered in natural history of Wegener’s granulomatosis.

Tamer Akça, Tahsin Çolak, Mehmet Çağlıkülekçi, Koray Öcal, Suha Aydın. Intestinal perforation in Wegener’s granulomatosis: a case report. Ulus Travma Acil Cerrahi Derg. 2005; 11(4): 348-351
Manuscript Language: English