NECROTIZING SOFT TISSUE INFECTIONS AND THE RISK FACTORS FOR MORTALITY

A retrospective review of the medical records of 11 patients between the years May 1988-June 1998 with the diagnosis of necrotizing fasciitis was performed. There were 2 females, and 9 males. Diabetes mellitus was the most common concomitant disease (6 patients, 55.5%), and the most common sites of origin of infection were the perineum (7 patients, 63 %). The mean number of surgical debridements were 5.1 (3-7). The mortality rate was 18.1% (2 patients). Age and sex of the patients, the presence of concomitant diseases, localization of the infection, timing of the surgery on the morbidity and mortality was evaluated. We conclude that extent and localization of the infection, presence of diabetes mellitus, presence of bacteriemia and prolonged immobilization influence the morbidity and mortality.

NEKROTÝZAN YUMUÞAK DOKU ENFEKSÝYONU VE MORTALÝTEYÝ ETKÝLEYEN FAKTÖRLER

Nekrotizan yumuþak doku enfeksiyonu (NYDE) tanýsý ile kliniðimizde Mayýs 1988 ile Aralýk 1998 tarihleri arasýnda tedavi edilen 11 hastanýn hastane kayýtlarý retrospektif olarak incelendi. Hastalardan 2'si kadýn 9'u erkekti. Hastalýðýn en sýk saptandýðý yer perianal bölge (7 hastada, %63), en sýk yandaþ hastalýk ise Diabet Mellitus (DM) (6 hasta, %55.5) olarak bulundu. Tüm hastalara ortalama 5.1 (3-7) kez cerrahi debridman uygulandý. Mortalite oraný %18.1 (2 hasta) olarak bulundu. Hastalarýn yaþ ve cinsiyeti, baþvuru anýndaki klinik ve laboratuvar parametreleri, yandaþ hastalýklarýn varlýðý, enfeksiyon lokalizasyonunun ve cerrahi tedavi zamanlamasýnýn morbidite ve mortalite üzerine olan etkisi deðerlendirildi. Enfeksiyon lokalizasyonu ve geniþliðinin, bakteriyemi varlýðýnýn, hastanýn diabetinin olmasýnýn ve uzamýþ inmobilizasyonun morbidite ve mortaliteyi etkilediði sonucuna varýldý.