Ulus Travma Acil Cerrahi Derg. 2020; 26(5): 777-783 | DOI: 10.14744/tjtes.2020.37862

Factors affecting the mortality at patients with burns: Single centre results

Ayetulah Temiz¹, Ayþe Albayrak², Rýfat Peksöz³, Esra Dýþcý⁴, Ercan Korkut⁴, Yusuf Tanrýkulu⁵, Yavuz Albayrak^4
1Department of General Surgery, Erzurum Regional Training and Research Hospital, Erzurum-Turkey
²Department of Infectious Diseases, Atatürk University Faculty of Medicine, Erzurum-Turkey
³Department of General Surgery, Malazgirt State Hospital, Muþ-Turkey
⁴Department of General Surgery, Atatürk University Faculty of Medicine, Erzurum-Turkey
⁵Department of General Surgery, KTO Karatay University Faculty of Medicine, Konya-Turkey

BACKGROUND: Burns are a primary cause of mortality along with the severe physical and psychological morbidities in patients and their families. Such kinds of injuries bring about considerable financial burdens due to the treatment processes and sequels. The present study aims to investigate the factors that affect the mortality of burns.
METHODS: The archives files of the patients admitted because of burn injuries in our burn centre between September 2008 and December 2016 were examined in this study. Some of the lab values, such as age, sex, percentage of total burn surface area (TBSA), referral status, burning site, degree of burns, time of admission to hospital, aetiology of burning, blood and blood products collection, complete blood count, routine biochemistry, coagulation parameters, C-reactive protein (CRP), sedimentation rate, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), were examined while evaluating the patients’ mortalities.
RESULTS: A total of 133 patients were included in this study. The patient’s age (p=0.001), the degree of burns (p<0.001), surface area of burns (p<0.001), the time of hospital admission (p<0.001), burning aetiology (p=0.006), erythrocyte suspension, fresh frozen plasma, along with the administration of albumin transfusion (p<0.001), mean platelet volume (MPV) (p=0.028), NLR (p<0.001) and PLR (p<0.030) values were found to be associated with mortality in patients with burns.
CONCLUSION: In this study, age, burn grade, TBSA, hospital admission time, burn aetiology, erythrocyte, fresh frozen plasma and albumin transfusion, MPV, NLR and PLR values were found to be associated with mortality in patients with burns. With this study, it is possible to produce the treatment guidelines to reduce mortality by taking these parameters into consideration, which were determined to be associated with mortality while evaluating the patients with burns.

Keywords: Burn, mean platelet volume; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio.

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Yanýklý hastalarda mortaliteyi etkileyen faktörler: Tek merkez sonuçlarý

Ayetulah Temiz¹, Ayþe Albayrak², Rýfat Peksöz³, Esra Dýþcý⁴, Ercan Korkut⁴, Yusuf Tanrýkulu⁵, Yavuz Albayrak^4
1Erzurum Bölge Eðitim ve Araþtýrma Hastanesi, Genel Cerrahi Kliniði, Erzurum
²Atatürk Üniversitesi Týp Fakültesi, Enfeksiyon Hastalýklarý Anabilim Dalý, Erzurum
³Malazgirt Devlet Hastanesi, Genel Cerrahi Kliniði, Muþ
⁴Atatürk Üniversitesi Týp Fakültesi, Genel Cerrahi Anabilim Dalý, Erzurum
⁵KTO Karatay Üniversitesi Týp Fakültesi, Genel Cerrahi Anabilim Dalý, Konya

AMAÇ: Yanýklar, hasta ve ailelerine ciddi fiziksel ve psikolojik morbidite meydana getirmeleri yanýnda önemli bir mortalite nedenidir. Ayrýca bu tür yaralanmalar, tedavi süreçleri ve býraktýðý sekeller nedeniyle önemli mali yükler de getirmektedir. Bu çalýþmada amaç, yanýk mortalitesini etkileyen faktörleri belirlemektir.
GEREÇ VE YÖNTEM: Yanýk merkezimize Eylül 2008–Aralýk 2016 yýllarý arasýnda yanýk nedeni ile baþvuran hastalarýn kayýtlarý incelendi. Hastalarýn mortaliteleri deðerlendirilirken yaþ, cinsiyet, yanýk yüzey alaný yüzdesi, sevk durumu, yanma yeri, yanýk derecesi, hastaneye baþvuru için geçen süre, yanma etyolojisi, kan ve kan ürünleri alýp almamasý, tam kan sayýmý, rutin biyokimya, kuagülasyon parametreleri, C-reaktif protein (CRP), sedimentasyon hýzý, nötrofil lenfosit oraný (NLR) ve trombosit-lenfosit oraný (PLR) gibi bazý laboratuvar deðerleri incelendi.
BULGULAR: Toplam 133 hasta çalýþmaya dahil edildi. Hastanýn yaþý (p=0.001), yanýk derecesi (p<0.001), yanýk yüzey alaný (p<0.001), hastaneye baþvuru süresi (p<0.001), yanma etiyolojisi (p<0.001), eritrosit süspansiyonu, Taze Donmuþ Plazma ve albümin transfüzyonu verilmesi (p<0.001), MPV (p<0.001), NLR (p<0.001) ve PLR (p<0.001) deðerlerinin yanýk hastalarýnda mortalite ile iliþkili olduðu tespit edildi.
TARTIÞMA: Bu çalýþmada, hastanýn yaþý, yanýk derecesi, yanýk yüzey alaný, hastaneye baþvuru süresi, yanma etiyolojisi, eritrosit, TDP ve albümin transfüzyonu, MPV, NLR ve PLR deðerlerinin yanýk hastalarýnda mortalite ile iliþkili olduðu tespit edildi. Yaptýðýmýz bu çalýþma ile yanýk hastalarý deðerlendirilirken mortalite ile iliþkili tespit edilen bu parametreler göz önünde bulundurularak hastalarýn mortalitesini azaltacak tedavi rehberlerinin oluþturulmasý saðlanabilir.

Anahtar Kelimeler: Nötrofil lenfosit oraný, ortalama trombosit hacmi; trombosit-lenfosit oraný; yanýk.

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