Ulus Travma Acil Cerrahi Derg. 2020; 26(5): 735-741 | DOI: 10.14744/tjtes.2020.81783

Relationship of mortality with neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean platelet volume in patients undergoing acute abdominal surgery

Þükran Merve Çolakoðlu¹, Döndü Genç Moralar², Büþra Tok Çekmecelioðlu³, Gülsüm Oya Hergünsel^2
1Department of Anesthesia and Reanimation,University of Health Sciences, Gaziosmanpaþa Taksim Training and Research Hospital, Ýstanbul-Turkey
²Department of Anesthesia and Reanimation, University of Health Sciences, Bakýrköy Dr. Sadi Konuk Training and Research Hospital, Ýstanbul-Turkey
³Department of Anesthesia and Reanimation, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Ýstanbul-Turke

BACKGROUND: Acute abdominal surgery has a high rate of mortality and morbidity, and intensive care is often needed in the postoperative period. In intensive care units, various scoring systems are used to determine prognosis and mortality but are not sufficient to predict mortality and prognosis. For this purpose, easily applicable, effective methods are being investigated. In this study, we aimed to investigate the relationship between mortality and blood parameters, such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and mean platelet volume (MPV), in patients undergoing acute abdominal surgery.
METHODS: This study included a total of 249 patients who underwent acute abdominal surgery. The patients were divided into two groups as survivors (n=126) and non-survivors (n=123). The patient data were retrospectively analysed. The NLR, PLR, and MPV values were compared between the groups. Data including age, sex, Acute Physiology and Chronic Health Evaluation II-IV scores (APACHEII-IV), Sequential Organ Failure Assessment scores (SOFA), Glasgow Coma Scale were assessed.
RESULTS: The mortality rate was 49.4% in our study. There was no statistically significant difference in the NLR and PLR values between the groups. However, MPV was significantly higher in the non-survivors group (p<0.004).
CONCLUSION: Our study results showed that MPV values were significantly higher in the non-survivors following acute abdominal surgery, and NLR and PLR were not associated with mortality.

Keywords: Acute abdomen, intensive care unit; mean platelet volume; mortality; neutrophil/lymphocyte ratio; platelet/lymphocyte ratio.

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Akut karýn cerrahisi geçiren hastalarda, nötrofil-lenfosit oraný, trombosit-lenfosit oraný ve ortalama trombosit hacminin mortalite ile iliþkisi

Þükran Merve Çolakoðlu¹, Döndü Genç Moralar², Büþra Tok Çekmecelioðlu³, Gülsüm Oya Hergünsel^2
1Saðlýk Bilimleri Üniversitesi, Gaziosmanpaþa Taksim Eðitim ve Araþtýrma Hastanesi, Anestezi ve Reanimasyon Kliniði, Ýstanbul
²Saðlýk Bilimleri Üniversitesi, Bakýrköy Dr. Sadi Konuk Eðitim ve Araþtýrma Hastanesi, Anestezi ve Reanimasyon Kliniði, Ýstanbul
³Saðlýk Bilimleri Üniversitesi, Sultan Abdulhamid Han Eðitim ve Araþtýrma Hastanesi, Anestezi ve Reanimasyon Kliniði, Ýstanbul

AMAÇ: Akut karýn cerrahisi sonrasý yüksek oranda mortalite ve morbidite görülmekte, postoperatif dönemde sýklýkla yoðun bakým ihtiyacý olmaktadýr. Yoðun bakým ünitelerinde, prognoz ve mortaliteyi belirlemek amacýyla çeþitli skorlama sistemleri kullanýlmakta ancak mortalite ve prognozu öngörmede yeterli olmamaktadýr. Bu amaçla kolay uygulanabilir, etkin yöntemler araþtýrýlmaktadýr. Biz bu çalýþmada, akut karýn cerrahisi geçiren hastalarda nötrofil-lenfosit oraný (NLO), trombosit-lenfosit oraný (TLO) ve ortalama trombosit hacmi (OTH) gibi kan parametrelerinin mortalite ile iliþkisini araþtýrmayý amaçladýk.
GEREÇ VE YÖNTEM: Bu çalýþmaya, akut karýn ameliyatý geçiren 249 hasta alýndý. Hastalar sað kalan (n=126) ve ölenler (n=123) olarak iki gruba ayrýldý. Hasta verileri retrospektif olarak incelendi. NLO, TLO ve OTH deðerleri gruplar arasýnda karþýlaþtýrýldý. Yaþ, cinsiyet, Akut Fizyoloji ve Kronik Saðlýk Deðerlendirmesi II-IV skorlarý (APACHEII-IV), Sýralý Organ Yetmezliði Deðerlendirme skorlarý (SOFA), Glasgow Koma Skalasý gibi veriler deðerlendirildi.
BULGULAR: Çalýþmamýzda mortalite oraný %49.4 idi. NLO ve TLO deðerlerinde gruplar arasýnda istatistiksel olarak anlamlý fark yoktu. Ancak, OTH ölenler grubunda anlamlý olarak yüksek bulundu (p<0.004).
TARTIÞMA: Çalýþma sonuçlarýmýz akut karýn cerrahisi sonrasý hayatýný kaybedenlerde OTH deðerlerinin anlamlý derecede yüksek olduðunu ve NLO ve TLO’nýn mortalite ile iliþkili olmadýðýný göstermiþtir.

Anahtar Kelimeler: Akut karýn, bakým ünitesi; mortalite, nötrofil lenfosit oraný; ortalama trombosit hacmi; trombosit lenfosit oraný.

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