p-ISSN: 1306-696x | e-ISSN: 1307-7945
Volume : 8 Issue : 4 Year : 2023

Quick Search




SCImago Journal & Country Rank
Turkish Journal of Trauma and Emergency Surgery THE LEVELS OF SERUM INTERLEUKINE IN THE CHILDREN WITH TRAUMA [Ulus Travma Acil Cerrahi Derg]
Ulus Travma Acil Cerrahi Derg. 2002; 8(4): 224-228

THE LEVELS OF SERUM INTERLEUKINE IN THE CHILDREN WITH TRAUMA

Hayri Levent Yılmaz1, Mehmet Dokur2, Salih Çetiner3, Gülşah Şeydaoğlu4
1Çukurova Üniversitesi Tıp Fakültesi Acil Tıp Anabilim Dalı, Adana, Turkey, [email protected]
2Çukurova Üniversitesi Tıp Fakültesi Acil Tıp Anabilim Dalı, Turkey
3Çukurova Üniversitesi Tıp Fakültesi Merkez Laboratuvarı, Adana, Turkey
4Çukurova Üniversitesi Tıp Fakültesi Biyoistatistik Anabilim Dalı, Adana, Turkey

Background: We investigated the levels of IL-I, IL-2, IL-4, IL-6, IL-I0 and IL-12 in serum of the children with trauma and its relation with the severity of trauma.
Methods: We included 45 children with moderate or severe multipl trauma and 21 healthy children for control group to our study. The serum IL-I, IL-2, IL-4, IL-6, IL-IO and IL-12 were measured by micro ELISA.
Results: Wefound a statistically significant difference between the serum values of IL-l, IL-4, 1 L-6, IL-I0 in the children with trauma and healthy control group. A similar difference was also observed between the control group and the trauma group with injury severity score (ISS) £30 and also ISS 3 32. Serum values of IL-2 and IL-12 did not show significant difference between the groups. We detected a positive correlation between ISS and IL-l, IL-6, IL-I0 and IL-I2 (respectively r = 0,602, p = 0,000; r = 0,391, p = 0,008; r = 0,399, p = 0,007; r = 0,475, p = 0,001 ).
Conclusion: These results point out that serum IL-6, IL-I0, IL-12 and especially IL-l has a close relationship with the severity of the tissue damage after trauma.

Keywords: Child, cytokine, ISS, trauma, the severity of trauma

TRAVMALI ÇOCUKLARDA SERUM İNTERLÖKİN DÜZEYLERİ

Hayri Levent Yılmaz1, Mehmet Dokur2, Salih Çetiner3, Gülşah Şeydaoğlu4
1Çukurova Üniversitesi Tıp Fakültesi Acil Tıp Anabilim Dalı, Adana, Turkey, [email protected]
2Çukurova Üniversitesi Tıp Fakültesi Acil Tıp Anabilim Dalı, Turkey
3Çukurova Üniversitesi Tıp Fakültesi Merkez Laboratuvarı, Adana, Turkey
4Çukurova Üniversitesi Tıp Fakültesi Biyoistatistik Anabilim Dalı, Adana, Turkey


Hayri Levent Yılmaz, Mehmet Dokur, Salih Çetiner, Gülşah Şeydaoğlu. THE LEVELS OF SERUM INTERLEUKINE IN THE CHILDREN WITH TRAUMA. Ulus Travma Acil Cerrahi Derg. 2002; 8(4): 224-228
Manuscript Language: Turkish