Hızlı Arama
The hemostatic effect of calcium alginate in experimental splenic injury model.
Ali Kemal Taskin1, Mehmet Yasar1, Ismet Ozaydin1, Bulent Kaya2, Orhan Bat2, Seyit Ankarali3, Umran Yildirim4, Metin Aydin11Duzce University Medical Faculty Department Of General Surgery Duzce,turkey2Fatih Sultan Mehmet Training And Research Hospital Department Of General Surgery Istanbul-turkey
3Duzce Unıversıty Medıcal Faculty Department Of Physiology Duzce, Turkey
4Duzce Unıversıty Medıcal Faculty Department Of Pathology Duzce, Turkey
INTRODUCTION: We evaluated the effect of calcium alginate as a hemostatic agent in
splenic injury model.
MATERIAL AND METHOD: Experimental rats were divided into four groups. Group I:
Laparotomy was not performed. Only blood samples for bleeding time and hemogram was
taken. Group II: After laparotomy, the abdomen was closed without any splenic injury.
Group III: After laparotomy, splenic injury about 0.5 cm in depth and 0.3 cm in lenght was
created by standart Rochester pean forceps. Gauze dressing with serum physiologic about 2x2
cm in size was applied to the injured splenic tissue for 3 minutes Group IV: After laparotomy,
standart splenic injury about 0.5 cm in lenght and 0.3 cm in depth was also created in this
group. Calcium alginate wound dressing 1x1 cm in size was applied to the splenic
wound.Peroperative blood loss, pre and postoperative hemoglobulin and hematocrit values were calculated.
RESULTS: When comparing decline in hematorit values and peroperative bleeding amount
in between Group III and Group IV, Group IV has lower decline in hematocrit values and
peroperative bleeding amount (Table II,III). CONCLUSION: In conclusion, Calcium alginate has hemostatic capacity. It may be used in
splenic injuries specially for Grade I and II.
Makale Dili: İngilizce